I can't fish wading or even standing anymore due to MS, so I have to adapt. I sometimes use a pontoon boat or a kayak, but at other times I simply sit in a chair or my wheelchair on the beach and fish. It's possible and can even produce a fish now and then - even though I rarely catch anything these days.
More about my situation on http://globalflyfisher.com/fishbetter/when-lightning-strikes/
Thanks to Henning Eskol for filming and shooting stills.